Following a competitive application process sponsored by the National Institute of Mental Health (NIMH), the Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) initiative was launched. After 2 years of large consensus meetings, a five-site psychometric and validation study, complex intellectual property agreements, and an endorsement by NIMH and the U.S. Food and Drug Administration (FDA), the MATRICS Consensus Cognitive Battery (MCCB) was initially presented in a series of three articles in the Journal in 2008 (1–3). Since then, the MCCB has been evaluated and scrutinized in a way that few test assessment batteries have been. Over time its strengths and limitations have come into sharper focus, and we believe it is a good time to review what we know about the MCCB 6 years later.

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